Myeloid cells from human liver dataset

immature LAMs

Ontology Term: lipid-associated macrophageCL:4033086
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: TREM2+ macrophages
Category Class of which the cell type is a subclass.: macrophageCL:0000235
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: FN1, CST6, SPP1, MT1G, TREM2, GPNMB, SLC16A10, CD9, EMP1, APOC1
Canonical Marker Genes: CD9, TREM2, GPNMB, SPP1, FABP5
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: Marker genes are top 10 DEGs for this population compared with others in the UMAP (from Table S2 in publication).

Set of Labels Description: Annotation of cell types in dataset based on prior knowledge
Annotation Method: manual