snRNA-seq of human retina - retinal ganglion cell subset

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Cell Metadata

PG_ON

Ontology Term: parasol ganglion cell of retinaCL:4023189
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: M cell, M ganglion cell
Category Class of which the cell type is a subclass.: retinal ganglion cellCL:0000740
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ARPP21, CDH8, TMEM132D, SLC6A1, MAN1A1, ADRA1A, CHRNA2, IGFBP5, TNR, GABRA1, AC011995.2
Canonical Marker Genes: CHRNA2
Rationale: 99.7%PG-ON of the Sanes dataset; 99.9%PG_ON of the Shekhar dataset; 99.5%PG_ON of the macaque dataset; 96.6%Unassigned of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual

Ontology Term: parasol ganglion cell of retinaCL:4023189
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: M cell, M ganglion cell
Category Class of which the cell type is a subclass.: retinal ganglion cellCL:0000740
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ARPP21, CDH8, TMEM132D, SLC6A1, MAN1A1, ADRA1A, CHRNA2, IGFBP5, TNR, GABRA1, AC011995.2
Canonical Marker Genes: CHRNA2
Rationale: 99.7%PG-ON of the Sanes dataset; 99.9%PG_ON of the Shekhar dataset; 99.5%PG_ON of the macaque dataset; 96.6%Unassigned of the mouse dataset; Known markers are curated from human, macaque, and mouse markers.

Set of Labels Description: A total of 11 retinal ganglion cell clusters were identified from over 399K retinal ganglion cell nuclei in the current atlas. Utilizing previously characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual