Single cell atlas of the human retina - Retinal ganglion cell subclass

OPN4

Ontology Term

retinal ganglion cellCL:0000740

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

RGC, RGCs, ganglion cell of retina, gangliocyte

Category

Class of which the cell type is a subclass.

intrinsically photosensitive retinal ganglion cellsCL:0009004

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

AL445433.2, CAMK2A, CDH6, CHL1, CPA6, CPNE8, DMD, KIAA1217, KIRREL3, NDST4, OPRM1, PLPPR5, RASGRP1, TGFA

Canonical Marker Genes

unknown

Rationale

76.1%scRNA_hRGC5 of the Sanes dataset;81.9%nShekhar_RGC6 of the Shekhar dataset;83.9%macaque_RGC15 of the macaque dataset;98.2%mouse_7_Novel of the mouse dataset;Known markers are curated from human, macaque and mouse markers.

Inherited from author_cell_type

Set of Labels Description

A total of 15 retinal ganglion cell clusters is identified from over 99K retinal ganglion cell nulcei in the current atlas. Utilizing previoulsy characterized markers from macaque, 5 clusters can be annotated.

Annotation Method

manual