Single cell atlas of the human retina - Retinal ganglion cell subclass

HRGC9

Ontology Term: retinal ganglion cellCL:0000740
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: ganglion cell of retina, gangliocyte, RGCs, RGC
Category Class of which the cell type is a subclass.: retinal cellCL:0009004
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: ACTN2, ACVR1, ARHGAP10, CREB5, ELL2, FNIP2, HOMER1, HS3ST2, GAP43, LURAP1L-AS1, NREP, SLC35F2
Canonical Marker Genes: unknown
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: 83.5%scRNA_hRGC5 of the Sanes dataset;14.0%nShekhar_PG_ON of the Shekhar dataset;70.8%macaque_MG_ON of the macaque dataset;95.1%mouse_13_Novel of the mouse dataset;Known markers are curated from human, macaque and mouse markers.

Set of Labels Description: A total of 15 retinal ganglion cell clusters is identified from over 99K retinal ganglion cell nulcei in the current atlas. Utilizing previoulsy characterized markers from macaque, 5 clusters can be annotated.
Annotation Method: manual